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  Indian J Med Microbiol
 

Figure 5: (a) Magnetic resonance imaging with fluid-attenuated inversion recovery showing symmetrical white matter changes with nodularity. (b) Striatal bundles sample showing white matter fragments of neuroparenchyma infiltrated by atypical lymphoid cells. (c) High magnification showing neoplastic lymphoid cells and mitosis (arrows). (d) Angiocentric arrangement of tumor cells (circled). (e) Tumor cells are positive for leukocyte common antigen, CD20 (B-cell marker), Occasional reactive intermingled lymphocytes are CD3 (T cell marker positive). MIB-1 labeling is high (proliferative marker), the stroma shows reactive gliosis (glial fibrillary acidic protein)

Figure 5: (a) Magnetic resonance imaging with fluid-attenuated inversion recovery showing symmetrical white matter changes with nodularity. (b) Striatal bundles sample showing white matter fragments of neuroparenchyma infiltrated by atypical lymphoid cells. (c) High magnification showing neoplastic lymphoid cells and mitosis (arrows). (d) Angiocentric arrangement of tumor cells (circled). (e) Tumor cells are positive for leukocyte common antigen, CD20 (B-cell marker), Occasional reactive intermingled lymphocytes are CD3 (T cell marker positive). MIB-1 labeling is high (proliferative marker), the stroma shows reactive gliosis (glial fibrillary acidic protein)